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With the aim to systematically describe the polymorphic miRNA regulome, we reviewed existing studies investigating miRNA-associated genetic variability and organized polymorphisms within miRNA regulome into four categories.

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Additionally, to supplement less explored categories so far, we developed two catalogs containing genetic variants related to miRNA silencing machinery.

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Genetic variability of microRNA regulome in human

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Additionally, to supplement less explored categories so far, we developed two catalogs containing genetic variants related to miRNA silencing machinery.

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Description: Additional Supporting Information may be found in the online version of this article:. The lack of this knowledge makes it difficult to understand, which alterations affect miRNA processing — whether they are structural alterations or sequence polymorphisms.

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